ERA4Health Joint Transnational Call (JTC) 2026

METABO-PREDICT

Metabolic Phenotyping for Predicting Weight Loss Response: A Translational Human-Mouse Approach

Prevention of unhealthy weight gain and/or obesity (PREVENT-OO)

Primary Objective

To test the hypothesis that baseline diet-induced thermogenesis (DIT), measured by the low-protein meal test (LPMT), predicts 12-month weight loss in patients treated with GLP-1 receptor agonists (Semaglutide or Tirzepatide).

120

Patients

€1.68M

Budget

5

Partners

36 months

Duration

Consortium Partners
Five leading European research institutions across 5 countries
DECoordinator

Dr. Tim Hollstein

University Hospital Schleswig-Holstein

40 patients€400k
ES

Dr. Guillermo Sánchez Delgado

University of Granada

40 patients€250k
NL

Prof. Guy Plasqui

Maastricht University

40 patients€350k
BE

Prof. Sebastiaan Dalle

University of Antwerp

0 patients€350k
FR

Dr. Cédric Moro

INSERM I2MC Toulouse

0 patients€250k